CYP27B1

gene product
CYP1, P450c1, PDDR, VDD1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
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antibodies-online
32 antibodies
Invitrogen Antibodies
3 antibodies
Acris Antibodies GmbH
2 antibodies
Abgent
2 antibodies
Aviva Systems Biology
2 antibodies
Biorbyt
12 antibodies
GeneTex
1 antibody
Novus Biologicals
1 antibody
OriGene
1 antibody
LifeSpan BioSciences, Inc.
44 antibodies
NSJ Bioreagents
1 antibody
St John's Laboratory
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Boster Biological Technology
1 antibody
Abnova Corporation
1 antibody
MyBioSource
5 antibodies
Creative Biolabs
3 antibodies
United States Biological
10 antibodies
Bioss
3 antibodies
Creative Diagnostics
1 antibody
EMD Millipore
1 antibody