Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60735 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- NLGN3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human NLGN3
- Description
- Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1¡Â binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses .
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of NLGN3 pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysate