abx030249

antibody from Abbexa
Targeting: PCDHGB2 PCDH-GAMMA-B2
Provider product page for abx030249
No application information provided.

Antibody data

Product number
abx030249 - Provider product page
Provider
Abbexa
Product name
Protocadherin Gamma-B2 (PCDHGB2) Antibody
Antibody type
Polyclonal
Description
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
80 µl
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
PCDHGB2 protein structure - abx030249 shown in red.