CABT-BL3273

antibody from Creative Diagnostics

Targeting: SELENON MDRS1, RSMD1, RSS, SELN, SEPN1

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL3273

Provider

Creative Diagnostics

Product name

Anti-SEPN1 (aa 507-557) polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.