Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN954715 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Selenoprotein N, 1 (SEPN1) (AA 416-445), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column followed by peptide Affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 416-445, C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references A mutation in the SEPN1 selenocysteine redefinition element (SRE) reduces selenocysteine incorporation and leads to SEPN1-related myopathy.
Oxidative stress in SEPN1-related myopathy: from pathophysiology to treatment.
Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle.
Maiti B, Arbogast S, Allamand V, Moyle MW, Anderson CB, Richard P, Guicheney P, Ferreiro A, Flanigan KM, Howard MT
Human mutation 2009 Mar;30(3):411-6
Human mutation 2009 Mar;30(3):411-6
Oxidative stress in SEPN1-related myopathy: from pathophysiology to treatment.
Arbogast S, Beuvin M, Fraysse B, Zhou H, Muntoni F, Ferreiro A
Annals of neurology 2009 Jun;65(6):677-86
Annals of neurology 2009 Jun;65(6):677-86
Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle.
Jurynec MJ, Xia R, Mackrill JJ, Gunther D, Crawford T, Flanigan KM, Abramson JJ, Howard MT, Grunwald DJ
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 26;105(34):12485-90
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 26;105(34):12485-90
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC