CABT-BL1124

antibody from Creative Diagnostics

Targeting: COQ10B FLJ13448

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL1124

Provider

Creative Diagnostics

Product name

Anti-COQ10B (aa 50-150) polyclonal antibody

Antibody type

Polyclonal

Description

COQ10 (Coenzyme Q10) is found in a wide variety of foods and is synthesized in all tissues. The de novo biosynthesis of COQ10, from its precursor tyrosine, is a multistage process that requires at least eight vitamins and several trace elements. More complex enzymes have an absolute dependancy on 'cofactors', a large group of molecules to which the coenzymes belong, for their catalyitic function. Coenzyme Q10 is the cofactor for, but not limited to, several mitochondrial enzymes that are central to the supply of adenosine triphosphate (ATP). In addition, COQ10 in its reduced form is a potent antioxidant, and in this capacity, a reduction in COQ10 levels are associtated with a variety of degenerative process including skin aging and neurodegenerative conditions such as Alzhiemer's, Huntingdon's and Parkinson's diseases.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.