23449-1-AP
antibody from Proteintech Group
Targeting: UBQLN2
Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 23449-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- UBQLN2 antibody
- Antibody type
- Polyclonal
- Description
- UBQLN2 antibody (Cat. #23449-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.
Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Higgins NR, Greenslade JE, Wu JJ, Miranda E, Galliciotti G, Monteiro MJ
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12948
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12948
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.
Dubos A, Castells-Nobau A, Meziane H, Oortveld MA, Houbaert X, Iacono G, Martin C, Mittelhaeuser C, Lalanne V, Kramer JM, Bhukel A, Quentin C, Slabbert J, Verstreken P, Sigrist SJ, Messaddeq N, Birling MC, Selloum M, Stunnenberg HG, Humeau Y, Schenck A, Herault Y
Human molecular genetics 2015 Dec 1;24(23):6736-55
Human molecular genetics 2015 Dec 1;24(23):6736-55
Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C
Journal of neurochemistry 2014 Apr;129(1):99-106
Journal of neurochemistry 2014 Apr;129(1):99-106
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 23449-1-AP(UBQLN2 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBQLN2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human UBQLN2. This antibody recognizes human, rat antigen. The UBQLN2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.