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Flow cytometry
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 137303 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#137303, RRID:AB_10550804
- Product name
- LEAF™ Purified anti-mouse/human CD351 (Fcá/µ receptor) [TX61]
- Antibody type
- Monoclonal
- Antigen
- mFcα/µ receptor transfected Ba/F3 cells
- Description
- Fcα/µ receptor (Fcα/µR), CD351, is a type I transmembrane protein with an Ig-like domain in extracellular portion. It is a novel Fc receptor for IgM and IgA. Fcα/µ receptor mRNA has been found in thymus, spleen, liver, kidney, intestines, testes, placenta, and T cell leukemia cell lines. Fcα/µ receptor protein expression is detected on B cells, macrophages, and activated T cells. Fcα/µ receptor mediates primary B lymphocyte endocytosis of IgM-coated Staphylococcus aureus. It is involved in the primary stages of the immune response to microbes.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4 °C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Con-A stimulated C57BL/6 splenocytes (3 days) were stained with CD3 APC and CD351 (clone TX-61) PE (top) or mouse IgG1, k (bottom).
- Conjugate
- Unconjugated
