BS8397

antibody from Bioworld Technology, Inc
Targeting: MSRB1 SelR, SelX, SepR, SEPX1
Provider product page for BS8397
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8397 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SEPX1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SEPX1.
Description
Selenium is an essential trace element that is incorporated as selenocysteine into the primary structure of selenoproteins. Nutritional deficiency of selenium decreases selenoprotein concentrations and leads to pathologic conditions. Most of the known selenoproteins are members of the glutathione peroxidase or iodothyronine deiodinase families. Selenoprotein P (SEPP1) is a major selenoprotein that is not a member of those families. It is an extracellular glycoprotein that is present in several isoforms and is the only selenoprotein known to contain multiple selenocysteine residues. SECIS elements form stem-loop structures in the 3' untranslated regions (UTR) of eukaryotic mRNAs that encode selenoproteins. The Selenoprotein W SECIS elements contain an additional highly conserved base-paired stem that may prevent inappropriate selenocysteine incorporation at the UGA stop codons. Selenoprotein R, also designated methionine-R-sulfoxide reductase or Selenoprotein X1, is a zinc binding protein. The gene encoding for Selenoprotein R contains seleno-cysteine, which is encoded by the usual stop codon TGA at the active site. Selenoprotein R may play a role in protection against oxidative stress.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MSRB1 protein structure - BS8397 shown in red.