AMAb91639

antibody from Atlas Antibodies

Targeting: PLP1 GPM6C, PLP, SPG2

Antibody data

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Validation data

Product number: AMAb91639 - Provider product page
Provider: Atlas Antibodies
Product name: Anti-PLP1
Antibody type: Monoclonal
Description: Monoclonal Antibody against Human PLP1, Clone ID: CL10622, Gene description: Proteolipid protein 1, Alternative Gene Names: GPM6C, PLP, SPG2, Validated applications: IHC, Uniprot ID: P60201, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Reactivity: Human, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: CL10622
Vial size: 100 µl
Concentration: 1.0 mg/ml
Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

PLP1 protein structure - AMAb91639 shown in red.

Enhanced validation

Submitted by: Atlas Antibodies (provider)
Enhanced method: Orthogonal validation
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Experimental details: Immunohistochemistry analysis in human cerebral cortex and tonsil tissues using AMAb91639 antibody. Corresponding PLP1 RNA-seq data are presented for the same tissues.
Sample type: Human
Protocol: Protocol
Orthogonal method: Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human cerebral cortex shows strong positivity in myelinated neural fibers.
Sample type: Human
Protocol: Protocol

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human cerebellum shows strong positivity in myelinated neuronal processes.
Sample type: Human
Protocol: Protocol

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human kidney shows no positivity as expected.
Sample type: Human
Protocol: Protocol

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human tonsil shows no positivity in lymphoid cells as expected.
Sample type: Human
Protocol: Protocol

Supportive validation

Submitted by: Atlas Antibodies (provider)
Main image
Experimental details: Immunohistochemical staining of rat cerebral cortex shows strong positivity in myelinated neuronal processes and in oligodendrocytes cell bodies.
Sample type: Rat
Protocol: Protocol