Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11179-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11179-1-AP, RRID:AB_2204687
- Product name
- TIMM8A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TIMM8A antibody (Cat. #11179-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Stress response silencing by an E3 ligase mutated in neurodegeneration.
Functional analysis of a novel mutation in the TIMM8A gene that causes deafness-dystonia-optic neuronopathy syndrome.
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.
Haakonsen DL, Heider M, Ingersoll AJ, Vodehnal K, Witus SR, Uenaka T, Wernig M, Rapé M
Nature 2024 Feb;626(8000):874-880
Nature 2024 Feb;626(8000):874-880
Functional analysis of a novel mutation in the TIMM8A gene that causes deafness-dystonia-optic neuronopathy syndrome.
Neighbors A, Moss T, Holloway L, Yu SH, Annese F, Skinner S, Saneto R, Steet R
Molecular genetics & genomic medicine 2020 Mar;8(3):e1121
Molecular genetics & genomic medicine 2020 Mar;8(3):e1121
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
Kang Y, Anderson AJ, Jackson TD, Palmer CS, De Souza DP, Fujihara KM, Stait T, Frazier AE, Clemons NJ, Tull D, Thorburn DR, McConville MJ, Ryan MT, Stroud DA, Stojanovski D
eLife 2019 Nov 4;8
eLife 2019 Nov 4;8
Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.
Sun Y, Li T, Xie C, Xu Y, Zhou K, Rodriguez J, Han W, Wang X, Kroemer G, Modjtahedi N, Blomgren K, Zhu C
Cell death & disease 2017 May 11;8(5):e2781
Cell death & disease 2017 May 11;8(5):e2781
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The TIMM8A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TIMM8A. This antibody recognizes human, mouse, rat antigen. The TIMM8A antibody has been validated for the following applications: ELISA, WB analysis.