Tissue expression
Cell line expression
Protein structure
MT1A
Metallothionein 1AMT1, MT1S
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. [provided by RefSeq, Sep 2017]
Top validated antibodies |
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Invitrogen Antibodies | MA1-25479 | 2 references | Monoclonal |
WB
IHC |
|
Novus Biologicals | H00004489-B01P-50ug | 1 references | Polyclonal |
WB
|
|
Cusabio Biotech Co., Ltd | CSB-PA17444A0Rb | Polyclonal |
EL
IHC |
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LSBio | LS-C372663 | Polyclonal |
WB
EL
ICC
IHC |
||
Abnova Corporation | MAB9787 | Monoclonal |
WB
EL
IP
|
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Supportive data in Antibodypedia
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Recommended by provider