BS60838

ADAM28 antibody from Bioworld Technology, Inc
ADAM23, eMDCII, MDC-Lm, MDC-Ls

Antibody data

Product number
BS60838
Provider
Bioworld Technology, Inc
Product name
ADAM28 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS60838
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ADAM28.
Description
The ADAM (a disintegrin and metalloprotease) protein family, which includes over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases, plays a role in cell-cell and cell-matrix interface related processes, including fertilization, muscle fusion, secretion of TNFÏ« (tumor necrosis factor Ï«), and modulation of the neurogenic function of Notch and Delta. The ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand), a cysteine-rich region, an epidermal growth factorlike domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in a wide range of mammalian tissues and several are abundantly expressed in the male reproductive tract. ADAM28, also designated MDC-L,is more closely related to snake venom metalloproteases (SVMPs) than to other ADAM family members. ADAM28 displays a high level of expression in lymphocytes and epididymis, and functions mainly on the cell surface, where it mediates cell adhesion through its binding to integrin Ï«4ÉÇ1. The gene encoding human ADAM28 maps to chromosome 8p21.2.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -