AP0245

antibody from Bioworld Technology, Inc
Targeting: HSPB1 CMT2F, Hs.76067, Hsp25, HSP27, HSP28
Provider product page for AP0245

Antibody data

Product number
AP0245 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#AP0245, RRID:AB_2797466
Product name
HSP27 (phospho S15) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human HSP27 around the phosphorylation site of Serine 15.
Description
Hsp27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis is induced by elevated temperature, as well as estrogen in hormone responsive cells. This protein is involved in stress resistance and actin organization. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSP's and mammalian a-crystalline lens protein. Because of the estrogen-responsive nature of Hsp27, this protein has been studied extensively in human estrogen-responsive tissues such as cervix, endometrium and breast tissue. This work has led to the suggestion that Hsp27 may be a useful marker in classifying various hormone sensitive tumors.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HSPB1 protein structure - AP0245 shown in red.