FNab05599

antibody from FineTest Biotech
Targeting: NDC80 HEC, HEC1, hsNDC80, KNTC2, TID3
Provider product page for FNab05599
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab05599 - Provider product page
Provider
FineTest Biotech
Product name
NDC80 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
NDC80 homolog, kinetochore complex
component
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
NDC80 protein structure - FNab05599 shown in red.