abx001030

antibody from Abbexa

Targeting: DAZL DAZH, DAZL1, DAZLA, MGC26406, SPGYLA

Western blot (Recommended by provider)

Antibody Data

Product number

abx001030

Provider

Abbexa

Product name

Deleted In Azoospermia-Like (DAZL) Antibody

Antibody type

Polyclonal

Description

DAZL Antibody is a Rabbit Polyclonal antibody against DAZL. The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.