APG01204G

antibody from Leading Biology

Targeting: PDCD4 H731

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APG01204G

Provider

Leading Biology

Product name

PDCD4 Antibody (aa210-221)

Antibody type

Polyclonal

Description

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Goat, Guinea Pig, Hamster, Horse, Rabbit, Simian, Xenopus

Host

Goat

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.