11-6007-25

antibody from ABEOMICS Inc.
Targeting: RBCK1 C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4
Provider product page for 11-6007-25

Antibody data

Product number
11-6007-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-HOIL-1L/RBCK1 Antibody
Antibody type
Polyclonal
Description
RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant HOIL-1
L/RBCK1 protein (amino acids 121-33
3) was used as the immunogen for th
is antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
RBCK1 protein structure - 11-6007-25 shown in red.