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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN359009 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nuclear Receptor Subfamily 4, Group A, Member 2 (NR4A2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the N-terminal region of human NURR1 (NR4A2).
- Description
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells.
Nur77 family of nuclear hormone receptors.
Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells.
Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs.
cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line.
NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.
Perlmann T, Wallén-Mackenzie A
Cell and tissue research 2004 Oct;318(1):45-52
Cell and tissue research 2004 Oct;318(1):45-52
Nur77 family of nuclear hormone receptors.
Hsu HC, Zhou T, Mountz JD
Current drug targets. Inflammation and allergy 2004 Dec;3(4):413-23
Current drug targets. Inflammation and allergy 2004 Dec;3(4):413-23
Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells.
Wallen-Mackenzie A, Mata de Urquiza A, Petersson S, Rodriguez FJ, Friling S, Wagner J, Ordentlich P, Lengqvist J, Heyman RA, Arenas E, Perlmann T
Genes & development 2003 Dec 15;17(24):3036-47
Genes & development 2003 Dec 15;17(24):3036-47
Molecular cloning of the human Nurr1 gene: characterization of the human gene and cDNAs.
Ichinose H, Ohye T, Suzuki T, Sumi-Ichinose C, Nomura T, Hagino Y, Nagatsu T
Gene 1999 Apr 16;230(2):233-9
Gene 1999 Apr 16;230(2):233-9
cDNA cloning of a NGFI-B/nur77-related transcription factor from an apoptotic human T cell line.
Okabe T, Takayanagi R, Imasaki K, Haji M, Nawata H, Watanabe T
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 15;154(8):3871-9
Journal of immunology (Baltimore, Md. : 1950) 1995 Apr 15;154(8):3871-9
NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.
Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA
Molecular endocrinology (Baltimore, Md.) 1994 Nov;8(11):1583-91
Molecular endocrinology (Baltimore, Md.) 1994 Nov;8(11):1583-91
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of anti-NURR1(NR4A2) Pab in mouse brain tissue lysate. NURR1(NR4A2) (arrow) was detected using the purified Pab.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human brain tissue reacted with NURR1 (NR4A2) antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
