Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [6]
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- Product number
- NBP1-84717 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84717, RRID:AB_11031804
- Product name
- Rabbit Polyclonal AUTS2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human AUTS2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes.
Cerebral organoids model human brain development and microcephaly.
Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Oksenberg N, Haliburton GD, Eckalbar WL, Oren I, Nishizaki S, Murphy K, Pollard KS, Birnbaum RY, Ahituv N
Translational psychiatry 2014 Sep 2;4:e431
Translational psychiatry 2014 Sep 2;4:e431
Cerebral organoids model human brain development and microcephaly.
Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA
Nature 2013 Sep 19;501(7467):373-9
Nature 2013 Sep 19;501(7467):373-9
Autism susceptibility candidate 2 (Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology.
Bedogni F, Hodge RD, Nelson BR, Frederick EA, Shiba N, Daza RA, Hevner RF
Gene expression patterns : GEP 2010 Jan;10(1):9-15
Gene expression patterns : GEP 2010 Jan;10(1):9-15
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Ek S, Andréasson U, Hober S, Kampf C, Pontén F, Uhlén M, Merz H, Borrebaeck CA
Molecular & cellular proteomics : MCP 2006 Jun;5(6):1072-81
Molecular & cellular proteomics : MCP 2006 Jun;5(6):1072-81
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining of human skeletal muscle shows very weak to negative nuclear positivity in monocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining of human prostate shows weak to moderate nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining of human skin shows moderate nuclear positivity.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining in mouse cortex.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: AUTS2 Antibody [NBP1-84717] - Staining of mouse embryo (E14) cortical plate shows strong nuclear positivity in neuronal cells.