PB9114
antibody from Boster Biological Technology
Targeting: NLRP3
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PB9114 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-CIAS1/NALP3/NLRP3 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for NALP3/NLRP3 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. NALP3/NLRP3 information: Molecular Weight: 118173 MW; Subcellular Localization: Cytoplasm ; Tissue Specificity: Expressed in blood leukocytes. Strongly expressed in polymorphonuclear cells and osteoblasts. Undetectable or expressed at a lower magnitude in B- and T-lymphoblasts, respectively. High level of expression detected in chondrocytes. Detected in non-keratinizing epithelia of oropharynx, esophagus and ectocervix and in the urothelial layer of the bladder.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Short-Chain Fatty Acids Weaken Ox-LDL-Induced Cell Inflammatory Injury by Inhibiting the NLRP3/Caspase-1 Pathway and Affecting Cellular Metabolism in THP-1 Cells.
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
LncRNA KCNQ1OT1 Mediates Pyroptosis in Diabetic Cardiomyopathy.
Yi C, Sun W, Ding L, Yan M, Sun C, Qiu C, Wang D, Wu L
Molecules (Basel, Switzerland) 2022 Dec 12;27(24)
Molecules (Basel, Switzerland) 2022 Dec 12;27(24)
Plumbagin attenuated oxygen-glucose deprivation/reoxygenation-induced injury in human SH-SY5Y cells by inhibiting NOX4-derived ROS-activated NLRP3 inflammasome.
Zhang Q, Zhao S, Zheng W, Fu H, Wu T, Hu F
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
Bioscience, biotechnology, and biochemistry 2020 Jan;84(1):134-142
LncRNA KCNQ1OT1 Mediates Pyroptosis in Diabetic Cardiomyopathy.
Yang F, Qin Y, Wang Y, Li A, Lv J, Sun X, Che H, Han T, Meng S, Bai Y, Wang L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1230-1244
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(4):1230-1244
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-CIAS1/NALP3 Picoband antibody, PB9114-1.jpgAll lanes: Anti CIAS1 (PB9114) at 0.5ug/mlWB: Recombinant Human CIAS1 Protein 0.5ngPredicted bind size: 37KDObserved bind size: 37KD
- Additional image