MAP1A

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]

Description

Microtubule associated protein 1A

Tissue specificity

Tissue enriched (brain)

Subcell location

Cytosol

Predicted location

Intracellular

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

15 (43510958 - 43531620)

Ensembl ID

ENSG00000166963  (ver. 103.38)

Orthologs

Mouse Map1a: ENSMUSG00000027254

UniProt

P78559

neXtProt

NX_P78559

Human splice variants
Mouse splice variants

Protein structure