Tissue expression
Cell line expression
Protein structure
MALRD1
MAM and LDL receptor class A domain containing 1bA265G8.2, C10orf112, Diet1
This gene encodes a conserved protein that features multiple MAM (meprin-A5-protein tyrosine phosphatase mu) and LDLR A2 (low density lipoprotein receptor A2) domains. Expression of this gene is enriched in the small intestine and is upregulated during differentiation of a human cell line that exhibits properties of intestinal epithelial cells. The encoded protein has been shown to modulate production of FGF19 in a human intestinal cell line and may regulate bile acid metabolism in the liver. A synergistic interaction between an allele of this gene and the APOE E4 allele is associated with an elevated risk of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2017]
Top validated antibodies |
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antibodies-online | ABIN4285924 | Polyclonal |
IHC
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Atlas Antibodies | HPA035732 | Polyclonal |
ICC
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Novus Biologicals | NBP2-14578 | Polyclonal |
IHC
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Invitrogen Antibodies | PA5-61350 | Polyclonal |
IHC
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Proteintech Group | 28213-1-AP | Polyclonal |
EL
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Supportive data in Antibodypedia
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Recommended by provider