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- Antigen structure
- References [22]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- NBP1-49461 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-49461, RRID:AB_10011569
- Product name
- Rabbit Polyclonal Stathmin-2/STMN2 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Gait Deficits and Loss of Striatal Tyrosine Hydroxlase/Trk-B are Restored Following 7,8-Dihydroxyflavone Treatment in a Progressive MPTP Mouse Model of Parkinson's Disease.
Collapsin Response Mediator Protein 4 (CRMP4) Facilitates Wallerian Degeneration and Axon Regeneration following Sciatic Nerve Injury.
Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration.
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia.
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.
Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.
Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models.
TRPV1 Agonist, Capsaicin, Induces Axon Outgrowth after Injury via Ca2+/PKA Signaling.
Facilitating effects of Buyang Huanwu decoction on axonal regeneration after peripheral nerve transection.
Whole-tissue 3D imaging reveals intra-adipose sympathetic plasticity regulated by NGF-TrkA signal in cold-induced beiging.
Epitranscriptomic m(6)A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
An Intrinsic Epigenetic Barrier for Functional Axon Regeneration.
CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins.
Low-cost multimodal light sheet microscopy for optically cleared tissues and living specimens.
Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.
Sustained GSK3 activity markedly facilitates nerve regeneration.
Dynamic regulation of SCG10 in regenerating axons after injury.
Injury-induced HDAC5 nuclear export is essential for axon regeneration.
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.
Massaquoi MS, Liguore WA, Churchill MJ, Moore C, Melrose HL, Meshul CK
Neuroscience 2020 May 1;433:53-71
Neuroscience 2020 May 1;433:53-71
Collapsin Response Mediator Protein 4 (CRMP4) Facilitates Wallerian Degeneration and Axon Regeneration following Sciatic Nerve Injury.
Girouard MP, Simas T, Hua L, Morquette B, Khazaei MR, Unsain N, Johnstone AD, Rambaldi I, Sanz RL, Di Raddo ME, Gamage KK, Yong Y, Willis DE, Verge VMK, Barker PA, Deppmann C, Fournier AE
eNeuro 2020 Mar Apr;7(2)
eNeuro 2020 Mar Apr;7(2)
Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration.
Pinto-Costa R, Sousa SC, Leite SC, Nogueira-Rodrigues J, Ferreira da Silva T, Machado D, Marques J, Costa AC, Liz MA, Bartolini F, Brites P, Costell M, Fässler R, Sousa MM
The Journal of clinical investigation 2020 Apr 1;130(4):2024-2040
The Journal of clinical investigation 2020 Apr 1;130(4):2024-2040
Circ-Spidr enhances axon regeneration after peripheral nerve injury.
Mao S, Huang T, Chen Y, Shen L, Zhou S, Zhang S, Yu B
Cell death & disease 2019 Oct 17;10(11):787
Cell death & disease 2019 Oct 17;10(11):787
Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia.
Carlin D, Halevi AE, Ewan EE, Moore AM, Cavalli V
eNeuro 2019 May Jun;6(3)
eNeuro 2019 May Jun;6(3)
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.
Holland SD, Ramer LM, McMahon SB, Denk F, Ramer MS
eNeuro 2019 Mar-Apr;6(2)
eNeuro 2019 Mar-Apr;6(2)
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.
Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, Rigo F, Da Cruz S, Ravits J, Lagier-Tourenne C, Cleveland DW
Nature neuroscience 2019 Feb;22(2):180-190
Nature neuroscience 2019 Feb;22(2):180-190
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair.
Klim JR, Williams LA, Limone F, Guerra San Juan I, Davis-Dusenbery BN, Mordes DA, Burberry A, Steinbaugh MJ, Gamage KK, Kirchner R, Moccia R, Cassel SH, Chen K, Wainger BJ, Woolf CJ, Eggan K
Nature neuroscience 2019 Feb;22(2):167-179
Nature neuroscience 2019 Feb;22(2):167-179
Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.
Davies AJ, Kim HW, Gonzalez-Cano R, Choi J, Back SK, Roh SE, Johnson E, Gabriac M, Kim MS, Lee J, Lee JE, Kim YS, Bae YC, Kim SJ, Lee KM, Na HS, Riva P, Latremoliere A, Rinaldi S, Ugolini S, Costigan M, Oh SB
Cell 2019 Feb 7;176(4):716-728.e18
Cell 2019 Feb 7;176(4):716-728.e18
Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models.
Hutson TH, Kathe C, Palmisano I, Bartholdi K, Hervera A, De Virgiliis F, McLachlan E, Zhou L, Kong G, Barraud Q, Danzi MC, Medrano-Fernandez A, Lopez-Atalaya JP, Boutillier AL, Sinha SH, Singh AK, Chaturbedy P, Moon LDF, Kundu TK, Bixby JL, Lemmon VP, Barco A, Courtine G, Di Giovanni S
Science translational medicine 2019 Apr 10;11(487)
Science translational medicine 2019 Apr 10;11(487)
TRPV1 Agonist, Capsaicin, Induces Axon Outgrowth after Injury via Ca2+/PKA Signaling.
Frey E, Karney-Grobe S, Krolak T, Milbrandt J, DiAntonio A
eNeuro 2018 May-Jun;5(3)
eNeuro 2018 May-Jun;5(3)
Facilitating effects of Buyang Huanwu decoction on axonal regeneration after peripheral nerve transection.
Kim KJ, Namgung U
Journal of ethnopharmacology 2018 Mar 1;213:56-64
Journal of ethnopharmacology 2018 Mar 1;213:56-64
Whole-tissue 3D imaging reveals intra-adipose sympathetic plasticity regulated by NGF-TrkA signal in cold-induced beiging.
Cao Y, Wang H, Zeng W
Protein & cell 2018 Jun;9(6):527-539
Protein & cell 2018 Jun;9(6):527-539
Epitranscriptomic m(6)A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.
Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong SZH, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, Wu H, Shen B, Zhuang X, He C, Liu K, Song H, Ming GL
Neuron 2018 Jan 17;97(2):313-325.e6
Neuron 2018 Jan 17;97(2):313-325.e6
An Intrinsic Epigenetic Barrier for Functional Axon Regeneration.
Weng YL, An R, Cassin J, Joseph J, Mi R, Wang C, Zhong C, Jin SG, Pfeifer GP, Bellacosa A, Dong X, Hoke A, He Z, Song H, Ming GL
Neuron 2017 Apr 19;94(2):337-346.e6
Neuron 2017 Apr 19;94(2):337-346.e6
CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins.
Chen L, Liu Z, Zhou B, Wei C, Zhou Y, Rosenfeld MG, Fu XD, Chisholm AD, Jin Y
eLife 2016 Jun 2;5
eLife 2016 Jun 2;5
Low-cost multimodal light sheet microscopy for optically cleared tissues and living specimens.
Rouger V, Alchini R, Kazarine A, Gopal AA, Girouard MP, Fournier AE, Wiseman PW
Journal of biomedical optics 2016 Dec 1;21(12):126008
Journal of biomedical optics 2016 Dec 1;21(12):126008
Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.
Valakh V, Frey E, Babetto E, Walker LJ, DiAntonio A
Neurobiology of disease 2015 May;77:13-25
Neurobiology of disease 2015 May;77:13-25
Sustained GSK3 activity markedly facilitates nerve regeneration.
Gobrecht P, Leibinger M, Andreadaki A, Fischer D
Nature communications 2014 Jul 31;5:4561
Nature communications 2014 Jul 31;5:4561
Dynamic regulation of SCG10 in regenerating axons after injury.
Shin JE, Geisler S, DiAntonio A
Experimental neurology 2014 Feb;252:1-11
Experimental neurology 2014 Feb;252:1-11
Injury-induced HDAC5 nuclear export is essential for axon regeneration.
Cho Y, Sloutsky R, Naegle KM, Cavalli V
Cell 2013 Nov 7;155(4):894-908
Cell 2013 Nov 7;155(4):894-908
Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.
Shin JE, Cho Y, Beirowski B, Milbrandt J, Cavalli V, DiAntonio A
Neuron 2012 Jun 21;74(6):1015-22
Neuron 2012 Jun 21;74(6):1015-22
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Stathmin-2/STMN2 Antibody [NBP1-49461] - Analysis of endogenous STMN2 in mouse dorsal root ganglia (DRG) neurons. A partial siRNA knockdown was used in the second lane. NBP1-49461 was used at a dilution of 1:1000. Image courtesy of Dr. Jung Eun Shin.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Stathmin-2/STMN2 Antibody [NBP1-49461] - Analysis of STMN2 in HEK293T cells transfected with GFP or a GFP-STMN2 fusion. NBP1-49461 was used at a dilution of 1:4000. Image courtesy of Dr. Jung Eun Shin.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: Stathmin-2/STMN2 Antibody [NBP1-49461] - Stathmin-2/STMN2 immunoreactivity at the trigeminal root entry zone (antibody diluted 1:1000, tissue taken from a mouse with experimental autoimmune encephalomyelitis). Image from verified customer review.
