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Protein structure
SCN5A
Sodium voltage-gated channel alpha subunit 5CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NB110-61010 |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
RA
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| Proteintech Group | 23016-1-AP |
10 references | Polyclonal |
WB
EL
IHC
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| GeneTex | GTX54803 |
Polyclonal |
WB
ICC
IHC
FC
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| antibodies-online | ABIN269816 |
1 references | Polyclonal |
WB
EL
IHC
|
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| LSBio | LS-C826030 |
Polyclonal |
WB
EL
IHC
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