10-4163

antibody from ABEOMICS Inc.
Targeting: FOXO1 FKH1, FKHR, FOXO1A
Provider product page for 10-4163

Antibody data

Product number
10-4163 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-FOXO1 Antibody
Antibody type
Monoclonal
Description
FOXO1 is one of the fox proteins playing pivotal roles in several human intracellular pathways. These proteins are transcription factors acting as nuclear regulator of transcriptional activity of a number of metabolic processes such as the cellular response to oxidative stress. FOXO1 protein response to oxidative stress may be linked to Alzheimer's disease (AD) by means of insulin brain resistance. FOXO1 plays a critical role in establishing and maintaining the B cell specific differentiation program, but it is also responsible for cell death due to an inappropriate BCR signaling. This protein is highly expressed in B cells, is downregulated in Hodgkin and Reed-Sternberg (HRS) cells of cHL (Classical Hodgkin Lymphoma).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A full length recombinant FOXO1 pro
tein was used as the immunogen for
this antibody.
Isotype
IgG
Antibody clone number
ABM4E66
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
FOXO1 protein structure - 10-4163 shown in red.