Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [3]
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Validation data
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- Product number
- V2176 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- Cytokeratin 17 Antibody
- Antibody type
- Monoclonal
- Antigen
- The cytoskeletal fraction of rat colon epithelium was used as the immunogen for this Cytokeratin 17 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human, Rat, Bovine, Goat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- E3
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the Cytokeratin 17 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Morphological and functional characteristics of human gingival junctional epithelium.
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms.
Emergence of keratin 17 vs. loss of keratin 13: their reciprocal immunohistochemical profiles in oral carcinoma in situ.
Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations.
Immunoreactivity for epithelial and neuroendocrine antibodies are useful in the differential diagnosis of lung carcinomas.
A mutation in human keratin K6b produces a phenocopy of the K17 disorder pachyonychia congenita type 2.
Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture.
Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia.
Laminin and type VII collagen distribution in different types of human lung carcinoma: correlation with expression of keratins 14, 16, 17 and 18.
Basal cell-specific and hyperproliferation-related keratins in human breast cancer.
Jiang Q, Yu Y, Ruan H, Luo Y, Guo X
BMC oral health 2014 Apr 3;14:30
BMC oral health 2014 Apr 3;14:30
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms.
Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, Kayamori K, Katsube K, Yamaguchi A
Laboratory investigation; a journal of technical methods and pathology 2012 May;92(5):688-702
Laboratory investigation; a journal of technical methods and pathology 2012 May;92(5):688-702
Emergence of keratin 17 vs. loss of keratin 13: their reciprocal immunohistochemical profiles in oral carcinoma in situ.
Mikami T, Cheng J, Maruyama S, Kobayashi T, Funayama A, Yamazaki M, Adeola HA, Wu L, Shingaki S, Saito C, Saku T
Oral oncology 2011 Jun;47(6):497-503
Oral oncology 2011 Jun;47(6):497-503
Generation and characterization of epidermolysis bullosa simplex cell lines: scratch assays show faster migration with disruptive keratin mutations.
Morley SM, D'Alessandro M, Sexton C, Rugg EL, Navsaria H, Shemanko CS, Huber M, Hohl D, Heagerty AI, Leigh IM, Lane EB
The British journal of dermatology 2003 Jul;149(1):46-58
The British journal of dermatology 2003 Jul;149(1):46-58
Immunoreactivity for epithelial and neuroendocrine antibodies are useful in the differential diagnosis of lung carcinomas.
Lyda MH, Weiss LM
Human pathology 2000 Aug;31(8):980-7
Human pathology 2000 Aug;31(8):980-7
A mutation in human keratin K6b produces a phenocopy of the K17 disorder pachyonychia congenita type 2.
Smith FJ, Jonkman MF, van Goor H, Coleman CM, Covello SP, Uitto J, McLean WH
Human molecular genetics 1998 Jul;7(7):1143-8
Human molecular genetics 1998 Jul;7(7):1143-8
Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture.
Moll I
Archives of dermatological research 1996 Sep;288(10):604-10
Archives of dermatological research 1996 Sep;288(10):604-10
Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia.
Smedts F, Ramaekers F, Troyanovsky S, Pruszczynski M, Robben H, Lane B, Leigh I, Plantema F, Vooijs P
The American journal of pathology 1992 Mar;140(3):601-12
The American journal of pathology 1992 Mar;140(3):601-12
Laminin and type VII collagen distribution in different types of human lung carcinoma: correlation with expression of keratins 14, 16, 17 and 18.
Wetzels RH, Schaafsma HE, Leigh IM, Lane EB, Troyanovsky SM, Wagenaar SS, Vooijs GP, Ramaekers FC
Histopathology 1992 Apr;20(4):295-303
Histopathology 1992 Apr;20(4):295-303
Basal cell-specific and hyperproliferation-related keratins in human breast cancer.
Wetzels RH, Kuijpers HJ, Lane EB, Leigh IM, Troyanovsky SM, Holland R, van Haelst UJ, Ramaekers FC
The American journal of pathology 1991 Mar;138(3):751-63
The American journal of pathology 1991 Mar;138(3):751-63
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of human samples using Cytokeratin 17 antibody (E3).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of bladder carcinoma stained with Cytokeratin 17 antibody.
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC testing of cervical carcinoma stained with Cytokeratin 17 antibody.
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of FFPE human bladder carcinoma with Cytokeratin 17 antibody (clone E3).