DCABH-2650

antibody from Creative Diagnostics

Targeting: TTR CTS, CTS1, HsT2651, PALB

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DCABH-2650

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-2650, RRID:AB_2476541

Product name

Rabbit Anti-Human TTR monoclonal antibody, clone KN22-54

Antibody type

Monoclonal

Description

Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein). The gene encoding Prealbumin maps to human chromosome 18q12.1.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

KN22-54

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.