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- References [8]
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- Immunohistochemistry [5]
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- Product number
- NBP1-85816 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-85816, RRID:AB_11014863
- Product name
- Rabbit Polyclonal ATF3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human ATF3 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse, Rat, Feline
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references The role of Na(V) channels in synaptic transmission after axotomy in a microfluidic culture platform.
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.
Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors.
Microglial pannexin-1 channel activation is a spinal determinant of joint pain.
The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.
Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib.
Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network.
Opposing roles for calcineurin and ATF3 in squamous skin cancer.
Vysokov N, McMahon SB, Raouf R
Scientific reports 2019 Sep 9;9(1):12915
Scientific reports 2019 Sep 9;9(1):12915
An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle.
Holland SD, Ramer LM, McMahon SB, Denk F, Ramer MS
eNeuro 2019 Mar-Apr;6(2)
eNeuro 2019 Mar-Apr;6(2)
Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors.
Bianchetti E, Bates SJ, Carroll SL, Siegelin MD, Roth KA
Scientific reports 2018 Nov 26;8(1):17390
Scientific reports 2018 Nov 26;8(1):17390
Microglial pannexin-1 channel activation is a spinal determinant of joint pain.
Mousseau M, Burma NE, Lee KY, Leduc-Pessah H, Kwok CHT, Reid AR, O'Brien M, Sagalajev B, Stratton JA, Patrick N, Stemkowski PL, Biernaskie J, Zamponi GW, Salo P, McDougall JJ, Prescott SA, Matyas JR, Trang T
Science advances 2018 Aug;4(8):eaas9846
Science advances 2018 Aug;4(8):eaas9846
The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.
Wei S, Wang H, Lu C, Malmut S, Zhang J, Ren S, Yu G, Wang W, Tang DD, Yan C
The Journal of biological chemistry 2014 Mar 28;289(13):8947-59
The Journal of biological chemistry 2014 Mar 28;289(13):8947-59
Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib.
Edagawa M, Kawauchi J, Hirata M, Goshima H, Inoue M, Okamoto T, Murakami A, Maehara Y, Kitajima S
The Journal of biological chemistry 2014 Aug 1;289(31):21544-61
The Journal of biological chemistry 2014 Aug 1;289(31):21544-61
Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network.
Hai T, Jalgaonkar S, Wolford CC, Yin X
Methods in enzymology 2011;490:175-94
Methods in enzymology 2011;490:175-94
Opposing roles for calcineurin and ATF3 in squamous skin cancer.
Wu X, Nguyen BC, Dziunycz P, Chang S, Brooks Y, Lefort K, Hofbauer GF, Dotto GP
Nature 2010 May 20;465(7296):368-72
Nature 2010 May 20;465(7296):368-72
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ATF3 Antibody [NBP1-85816] - Staining of human fallopian tube shows moderate to strong nuclear positivity in a subset of glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ATF3 Antibody [NBP1-85816] - Staining of human urinary bladder shows moderate to strong nuclear positivity in epithelial cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ATF3 Antibody [NBP1-85816] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: ATF3 Antibody [NBP1-85816] - Staining of human skeletal muscle shows no nuclear positivity in myelopoietic cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: ATF3 Antibody [NBP1-85816] - Image was captured under an epi-fluorescent microscope. Alexa 488 conjugated rabbit antibody was used for the secondary antibody. Immunofluorescent signal was localized in the nucleus. Image submitted by a verified customer review.
