Antibody data
- Antibody Data
- Antigen structure
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- Product number
- FNab03489 - Provider product page
- Provider
- FineTest Biotech
- Product name
- GLRB antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1(PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability(PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488).
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
glycine receptor, beta
- Epitope
- IgG
- Isotype
- IgG
- Vial size
- 100¦Ìg
- Concentration
- Immunogen affinity purified
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
- Handling
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
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