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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- GTX101336 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX101336, RRID:AB_1240465
- Product name
- APP antibody [C2C3], C-term
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
Submitted references HIV-1 gag recruits PACSIN2 to promote virus spreading.
Upregulated BMP6 pathway involved in the pathogenesis of Aβ toxicity in vivo.
Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.
Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.
Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
Popov S, Popova E, Inoue M, Wu Y, Göttlinger H
Proceedings of the National Academy of Sciences of the United States of America 2018 Jul 3;115(27):7093-7098
Proceedings of the National Academy of Sciences of the United States of America 2018 Jul 3;115(27):7093-7098
Upregulated BMP6 pathway involved in the pathogenesis of Aβ toxicity in vivo.
Lin S, Wei L, Ping Y, Xia L, Xiao S
Neuroscience letters 2018 Jan 18;664:152-159
Neuroscience letters 2018 Jan 18;664:152-159
Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.
Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T
Neuroscience research 2015 May;94:1-9
Neuroscience research 2015 May;94:1-9
Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.
Yoshida H, Meng P, Matsumiya T, Tanji K, Hayakari R, Xing F, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Imaizumi T
Neuroscience research 2014 Feb;79:83-93
Neuroscience research 2014 Feb;79:83-93
Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
Meng P, Yoshida H, Matsumiya T, Imaizumi T, Tanji K, Xing F, Hayakari R, Dempoya J, Tatsuta T, Aizawa-Yashiro T, Mimura J, Kosaka K, Itoh K, Satoh K
Neuroscience research 2013 Feb;75(2):94-102
Neuroscience research 2013 Feb;75(2):94-102
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample(30 £gg of whole cell lysate)A:Hep G2(GTX27900)7.5% SDS PAGEGTX101336 diluted at 1:1500
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Sample (30 ug of whole cell lysate) A:NIH-3T3 7.5% SDS PAGE GTX101336 diluted at 1:1000
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Various whole cell extracts (30 £gg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with APP antibody [C2C3], C-term (GTX101336) diluted at 1:500.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- APP antibody [C2C3], C-term detects APP protein at cytoplasm by immunofluorescent analysis.Sample: SK-N-SH cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: APP protein stained by APP antibody [C2C3], C-term (GTX101336) diluted at 1:400.Blue: Hoechst 33342 staining.Scale bar = 10 £gm.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human tonsil, plasma cells, using APP(GTX101336) antibody(10 £gg/ml).
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- APP antibody [C2C3], C-term detects APP protein at cytoplasm in Rat brain by immunohistochemical analysis. Sample: Paraffin-embedded Rat brain. APP antibody [C2C3], C-term (GTX101336) diluted at 1:500.
