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- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
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- Product number
- NBP1-44047 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-44047, RRID:AB_2258341
- Product name
- Rabbit Polyclonal Abeta 40 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This polyclonal antibody has been imuunodepleted of all Abeta 40 1-42 reactivity.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.12 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references HHV-6A infection induces amyloid-beta expression and activation of microglial cells.
Endocytosis and Transcytosis of Amyloid-β Peptides by Astrocytes: A Possible Mechanism for Amyloid-β Clearance in Alzheimer's Disease.
Alzheimer's disease: genes, proteins, and therapy.
Stereochemical specificity of Alzheimer's disease beta-peptide assembly.
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Bortolotti D, Gentili V, Rotola A, Caselli E, Rizzo R
Alzheimer's research & therapy 2019 Dec 12;11(1):104
Alzheimer's research & therapy 2019 Dec 12;11(1):104
Endocytosis and Transcytosis of Amyloid-β Peptides by Astrocytes: A Possible Mechanism for Amyloid-β Clearance in Alzheimer's Disease.
Domínguez-Prieto M, Velasco A, Tabernero A, Medina JM
Journal of Alzheimer's disease : JAD 2018;65(4):1109-1124
Journal of Alzheimer's disease : JAD 2018;65(4):1109-1124
Alzheimer's disease: genes, proteins, and therapy.
Selkoe DJ
Physiological reviews 2001 Apr;81(2):741-66
Physiological reviews 2001 Apr;81(2):741-66
Stereochemical specificity of Alzheimer's disease beta-peptide assembly.
Esler WP, Stimson ER, Fishman JB, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE
Biopolymers 1999 May;49(6):505-14
Biopolymers 1999 May;49(6):505-14
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.
Glenner GG, Wong CW
Biochemical and biophysical research communications 1984 May 16;120(3):885-90
Biochemical and biophysical research communications 1984 May 16;120(3):885-90
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Abeta 40 Antibody [NBP1-44047] - 1-40(lane 1) and 1-42 (lane 2) ABeta peptides were run on a 16.5% TRIS/tricine gel and transferred to PVDF membrane. The peptide concentration was approximately 0.5ng/lane. The blot was incubated with affinity purified AB40 antibody at 1ug/ml, followed by an oat and rabbit -HRP antibody at 1:40,000 and developed using a standard chemiluminescence method. A single band is present only in lane 1 which contains the ABeta 1-40 peptide and no signal is found in lane 2 which contains the ABeta 1-42 peptide.
