60024

antibody from STEMCELL Technologies Inc

Targeting: THY1 CD90

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

60024

Provider

STEMCELL Technologies Inc

Product name

Anti-Rat CD90 Antibody, Clone OX-7

Antibody type

Monoclonal

Description

The OX-7 antibody reacts with rat CD90 (Thy-1) and mouse The OX-7 antibody reacts with rat CD90 (Thy-1) and mouse CD90.1 (Thy-1.1), the latter being an allelic form of CD90 expressed by mouse strains AKR/J, PL, and FVB/N. The OX-7 antibody does not react with CD90.2, which is expressed by many mouse strains, including CBA and BALB/c. CD90 is a GPI-linked membrane glycoprotein and member of the immunoglobulin superfamily. The 25 kDa core protein is N-glycosylated at three sites, giving rise to molecules with a range of molecular masses (25 - 37 kDa). In the rat, CD90 is expressed by several cell types, including hematopoietic stem cells, immature B cells, thymocytes and neurons. In mouse strains expressing CD90.1, it is found on early-stage hematopoietic cells in the bone marrow, thymocytes, and circulating mature T cells. The OX-7 antibody has been reported to induce leukocyte activation, glomerular nephritis, apoptosis in glomerular mesangial cells, and vascular permeability. This antibody clone has been verified for purity assessments of cells isolated from compatible mouse strains with EasySep™ kits, including EasySep™ Mouse T Cell Isolation Kit (Catalog #19851).

Reactivity

Mouse, Rat, Guinea Pig, Rabbit

Isotype

IgG

Vial size

500 µg

Storage

2 - 8°C