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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Flow cytometry [1]
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- Product number
- 328116 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#328116, RRID:AB_893430
- Product name
- Alexa Fluor® 647 anti-human CD90 (Thy1) [5E10]
- Antibody type
- Monoclonal
- Antigen
- HEL cells
- Description
- CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblast, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, inhibits hematopoietic stem cells proliferation and differentiation.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Multipotent stem cells from trabecular meshwork become phagocytic TM cells.
Du Y, Roh DS, Mann MM, Funderburgh ML, Funderburgh JL, Schuman JS
Investigative ophthalmology & visual science 2012 Mar;53(3):1566-75
Investigative ophthalmology & visual science 2012 Mar;53(3):1566-75
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- BioLegend (provider)
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- Experimental details
- Human erythroleukemia cell line (HEL) stained with 5E10 Alexa Fluor® 647
- Conjugate
- Red dye
