NMT2

This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Description

N-myristoyltransferase 2

Tissue specificity

Low tissue specificity

Subcell location

Golgi apparatus, Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

10 (15102584 - 15168693)

Ensembl ID

ENSG00000152465  (ver. 103.38)

Orthologs

Mouse Nmt2: ENSMUSG00000026643

UniProt

O60551

neXtProt

NX_O60551

Human splice variants
Mouse splice variants

Protein structure