BS1633

antibody from Bioworld Technology, Inc
Targeting: MT-ND4L MTND4L, NAD4L, ND4L
Provider product page for BS1633
Western blot

Antibody data

Product number
BS1633 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ND4L polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to amino acids 80-97 of Mouse ND4L.
Description
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 4L (ND4L) is most likely a component of the hydrophobic protein fragment of Complex I. Mutations in the gene encodiing for ND4 are implicated in Leber hereditary optic neuropathy, a rare condition that can cause loss of central vision.
Reactivity
Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MT-ND4L protein structure - BS1633 shown in red.