Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-233-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-233-C100, RRID:AB_2051313
- Product name
- Dnmt3b monoclonal antibody (52A1018)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 52A1018
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20¡C.
Submitted references Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein.
Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development.
An association of DNMT3b protein expression with P16INK4a promoter hypermethylation in non-smoking female lung cancer with human papillomavirus infection.
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells.
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer.
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription.
Carlone DL, Lee JH, Young SR, Dobrota E, Butler JS, Ruiz J, Skalnik DG
Molecular and cellular biology 2005 Jun;25(12):4881-91
Molecular and cellular biology 2005 Jun;25(12):4881-91
Stage-specific induction of DNA methyltransferases in olfactory receptor neuron development.
MacDonald JL, Gin CS, Roskams AJ
Developmental biology 2005 Dec 15;288(2):461-73
Developmental biology 2005 Dec 15;288(2):461-73
An association of DNMT3b protein expression with P16INK4a promoter hypermethylation in non-smoking female lung cancer with human papillomavirus infection.
Lin TS, Lee H, Chen RA, Ho ML, Lin CY, Chen YH, Tsai YY, Chou MC, Cheng YW
Cancer letters 2005 Aug 8;226(1):77-84
Cancer letters 2005 Aug 8;226(1):77-84
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells.
Kawasaki H, Taira K
Nature 2004 Sep 9;431(7005):211-7
Nature 2004 Sep 9;431(7005):211-7
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer.
Leu YW, Yan PS, Fan M, Jin VX, Liu JC, Curran EM, Welshons WV, Wei SH, Davuluri RV, Plass C, Nephew KP, Huang TH
Cancer research 2004 Nov 15;64(22):8184-92
Cancer research 2004 Nov 15;64(22):8184-92
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.
Weisenberger DJ, Velicescu M, Cheng JC, Gonzales FA, Liang G, Jones PA
Molecular cancer research : MCR 2004 Jan;2(1):62-72
Molecular cancer research : MCR 2004 Jan;2(1):62-72
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, Huang TH
Cancer research 2003 Oct 1;63(19):6110-5
Cancer research 2003 Oct 1;63(19):6110-5
The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription.
Santoro R, Li J, Grummt I
Nature genetics 2002 Nov;32(3):393-6
Nature genetics 2002 Nov;32(3):393-6
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of Dnmt3b in NIH 3T3 cell lysate using MAb to Dnmt3b (52A1018) (Prod. No. ALX-804-233)Êat 4µg/ml.