ABIN2845287

antibody from antibodies-online

Targeting: RAP1GDS1 SmgGDS

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN2845287

Provider

antibodies-online

Product name

anti-RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1) (AA 217-244), (Center) antibody

Antibody type

Polyclonal

Description

This antibody is purified through a protein A column, followed by peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

AA 217-244, Center

Antibody clone number

RB31690

Vial size

80 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells.

Schönherr C, Yang HL, Vigny M, Palmer RH, Hallberg B
Oncogene 2010 May 13;29(19):2817-30

---

Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis.

Branham MT, Bustos MA, De Blas GA, Rehmann H, Zarelli VE, Treviño CL, Darszon A, Mayorga LS, Tomes CN
The Journal of biological chemistry 2009 Sep 11;284(37):24825-39

---

Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

Tiwari S, Felekkis K, Moon EY, Flies A, Sherr DH, Lerner A
Blood 2004 Apr 1;103(7):2661-7

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

IHC