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- Antigen structure
- References [3]
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- Product number
- MA1-70053 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Complement C3b Monoclonal Antibody (6C9)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- MA1-70053 detects C3/C3b/iC3b in human and mouse samples. MA1-70053 has been successfully used in flow cytometry and ELISA procedures. The MA1-70053 immunogen is human C3. Store at 4ºC. For long term storage, aliquot and freeze unused portion at -20ºC in volumes appropriat for single usage. Avoid freeze/thaw cycles.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 6C9
- Vial size
- 250 µg
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Factor H Is Bound by Outer Membrane-Displayed Carbohydrate Metabolism Enzymes of Extraintestinal Pathogenic Escherichia coli and Contributes to Opsonophagocytosis Resistance in Bacteria.
All-trans retinoic acid protects mesenchymal stem cells from immune thrombocytopenia by regulating the complement-interleukin-1β loop.
TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.
Sun Y, Xu B, Zhuge X, Tang F, Wang X, Gong Q, Chen R, Xue F, Dai J
Frontiers in cellular and infection microbiology 2020;10:592906
Frontiers in cellular and infection microbiology 2020;10:592906
All-trans retinoic acid protects mesenchymal stem cells from immune thrombocytopenia by regulating the complement-interleukin-1β loop.
Zhu X, Wang Y, Jiang Q, Jiang H, Lu J, Wang Y, Kong Y, Chang Y, Xu L, Peng J, Hou M, Huang X, Zhang X
Haematologica 2019 Aug;104(8):1661-1675
Haematologica 2019 Aug;104(8):1661-1675
TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.
Shi J, Rose EL, Singh A, Hussain S, Stagliano NE, Parry GC, Panicker S
Blood 2014 Jun 26;123(26):4015-22
Blood 2014 Jun 26;123(26):4015-22
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometric analysis of C57BL/6 mouse thymocytes incubated with rabbit anti-mouse T cells and then incubated with fresh human serum were stained using a Complement C3b monoclonal antibody (Product # MA1-70053) (filled histogram) or mouse IgG1 isotype control (open histogram).
