Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21337-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- C3/C3b/C3c antibody
- Antibody type
- Polyclonal
- Description
- C3/C3b/C3c antibody (Cat. #21337-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exogenous Biological Renal Support Improves Kidney Function in Mice With Rhabdomyolysis-Induced Acute Kidney Injury.
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice.
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis.
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium.
Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.
Liu C, Chi K, Geng X, Hong Q, Mao Z, Huang Q, Liu D, Wang Y, Zhang Y, Zhou F, Cai G, Chen X, Sun X
Frontiers in medicine 2021;8:655787
Frontiers in medicine 2021;8:655787
Proteomic Landscape of Exosomes Reveals the Functional Contributions of CD151 in Triple-Negative Breast Cancer.
Li S, Li X, Yang S, Pi H, Li Z, Yao P, Zhang Q, Wang Q, Shen P, Li X, Ji J
Molecular & cellular proteomics : MCP 2021;20:100121
Molecular & cellular proteomics : MCP 2021;20:100121
Extracellular vesicles derived from CD73 modified human umbilical cord mesenchymal stem cells ameliorate inflammation after spinal cord injury.
Zhai X, Chen K, Yang H, Li B, Zhou T, Wang H, Zhou H, Chen S, Zhou X, Wei X, Bai Y, Li M
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Journal of nanobiotechnology 2021 Sep 8;19(1):274
Complement C3 Aggravates Post-epileptic Neuronal Injury Via Activation of TRPV1.
Jiang GT, Shao L, Kong S, Zeng ML, Cheng JJ, Chen TX, Han S, Yin J, Liu WH, He XH, Liu YM, Gongga L, Peng BW
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Neuroscience bulletin 2021 Oct;37(10):1427-1440
Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice.
Chen L, Yang N, Li Y, Li Y, Hong J, Wang Q, Liu K, Han D, Han Y, Mi X, Shi C, Zhou Y, Li Z, Liu T, Guo X
CNS neuroscience & therapeutics 2021 Nov;27(11):1374-1384
CNS neuroscience & therapeutics 2021 Nov;27(11):1374-1384
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
Aaron N, Kraakman MJ, Zhou Q, Liu Q, Costa S, Yang J, Liu L, Yu L, Wang L, He Y, Fan L, Hirakawa H, Ding L, Lo J, Wang W, Zhao B, Guo E, Sun L, Rosen CJ, Qiang L
eLife 2021 Jun 22;10
eLife 2021 Jun 22;10
Silencing of circIgf1r plays a protective role in neuronal injury via regulating astrocyte polarization during epilepsy.
Shao L, Jiang GT, Yang XL, Zeng ML, Cheng JJ, Kong S, Dong X, Chen TX, Han S, Yin J, Liu WH, He XH, He C, Peng BW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21330
Yak milk-derived exosomes alleviate lipopolysaccharide-induced intestinal inflammation by inhibiting PI3K/AKT/C3 pathway activation.
Gao HN, Hu H, Wen PC, Lian S, Xie XL, Song HL, Yang ZN, Ren FZ
Journal of dairy science 2021 Aug;104(8):8411-8424
Journal of dairy science 2021 Aug;104(8):8411-8424
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.
Cipriani V, Lorés-Motta L, He F, Fathalla D, Tilakaratna V, McHarg S, Bayatti N, Acar İE, Hoyng CB, Fauser S, Moore AT, Yates JRW, de Jong EK, Morgan BP, den Hollander AI, Bishop PN, Clark SJ
Nature communications 2020 Feb 7;11(1):778
Nature communications 2020 Feb 7;11(1):778
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
Alberts A, Klingberg A, Wessig AK, Combes C, Witte T, Brand K, Pich A, Neumann K
Scientific reports 2020 Apr 14;10(1):6391
Scientific reports 2020 Apr 14;10(1):6391
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis.
Deng S, Xu T, Fang Q, Yu L, Zhu J, Chen L, Liu J, Zhou R
Frontiers in immunology 2018;9:1063
Frontiers in immunology 2018;9:1063
4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells.
Linetsky M, Bondelid KS, Losovskiy S, Gabyak V, Rullo MJ, Stiadle TI, Munjapara V, Saxena P, Ma D, Cheng YS, Howes AM, Udeigwe E, Salomon RG
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Chemical research in toxicology 2018 Aug 20;31(8):666-679
Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease.
Zhang L, Song QF, Jin JJ, Huang P, Wang ZP, Xie XF, Gu XQ, Gao XJ, Jia HL
Cardiology in the young 2017 Nov;27(9):1786-1796
Cardiology in the young 2017 Nov;27(9):1786-1796
Serum estradiol levels in controlled ovarian stimulation directly affect the endometrium.
Ullah K, Rahman TU, Pan HT, Guo MX, Dong XY, Liu J, Jin LY, Cheng Y, Ke ZH, Ren J, Lin XH, Qiu XX, Wang TT, Huang HF, Sheng JZ
Journal of molecular endocrinology 2017 Aug;59(2):105-119
Journal of molecular endocrinology 2017 Aug;59(2):105-119
Identification of Potential Biomarkers for Rhegmatogenous Retinal Detachment Associated with Choroidal Detachment by Vitreous iTRAQ-Based Proteomic Profiling.
Wu Z, Ding N, Yu M, Wang K, Luo S, Zou W, Zhou Y, Yan B, Jiang Q
International journal of molecular sciences 2016 Dec 7;17(12)
International journal of molecular sciences 2016 Dec 7;17(12)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The C3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human C3. This antibody recognizes human antigen. The C3 antibody has been validated for the following applications: ELISA, WB analysis.