BS6716

antibody from Bioworld Technology, Inc
Targeting: PTPN2 PTPT, TC-PTP, TCELLPTP, TCPTP
Provider product page for BS6716
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6716 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PTPN2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PTPN2.
Description
T-cell protein tyrosine phosphatase (TC-PTP) is a non-transmembrane enzyme. The noncatalytic domain of TC-PTP is alternatively spliced to generate p45TC, which localizes to the nucleus, and p48TC, which contains a hydrophobic C-terminal tail and localizes to the ER. The C-terminal segment of p45TC regulates the activity of the catalytic domain through an intramolecular interaction. The p45TC variant of TC-PTP exits the nucleus upon EGF receptor activation and recognizes the EGF receptor and p52Shc cellular substrates.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PTPN2 protein structure - BS6716 shown in red.