MAB2739

antibody from Abnova Corporation

Targeting: PTPN2 PTPT, TC-PTP, TCELLPTP, TCPTP

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB2739

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB2739, RRID:AB_10633569

Product name

PTPN2 monoclonal antibody, clone T25-AF3B7

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against recombinant PTPN2.

Antibody clone number

T25-AF3B7

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease.

Doody KM, Bourdeau A, Tremblay ML
Immunological reviews 2009 Mar;228(1):325-41

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TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}.

Bourdeau A, Dubé N, Heinonen KM, Théberge JF, Doody KM, Tremblay ML
Blood 2007 May 15;109(10):4220-8

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Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP.

Galic S, Klingler-Hoffmann M, Fodero-Tavoletti MT, Puryer MA, Meng TC, Tonks NK, Tiganis T
Molecular and cellular biology 2003 Mar;23(6):2096-108

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunoblot analysis of cell lysates.Lane 1 : Bosc23 cell lysate.Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441 a. a.).Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPN2 (1-387E a. a.).Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.