BS4220

antibody from Bioworld Technology, Inc

Targeting: CASP8 Casp-8, FLICE, MACH, MCH5

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4220 - Provider product page
Provider: Bioworld Technology, Inc
Product name: Caspase 8 (phospho S347) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human Caspase-8 around the phosphorylation site of Serine 347.
Description: Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CASP8 protein structure - BS4220 shown in red.