FNab01294

antibody from FineTest Biotech

Targeting: CASP8 Casp-8, FLICE, MACH, MCH5

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ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

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Validation data

Product number: FNab01294 - Provider product page
Provider: FineTest Biotech
Product name: Caspase 8 antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibody can recognize pro-and cleaved-caspase 8.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: caspase 8, apoptosis-related cystei ne peptidase
Epitope: IgG1
Isotype: IgG
Antibody clone number: 2C2
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CASP8 protein structure - FNab01294 shown in red.