Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN392089 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 209-239), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 209-239, Center
- Antibody clone number
- RB03117
- Vial size
- 400 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering.
Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production.
Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.
Márquez JA, Smith CI, Petoukhov MV, Lo Surdo P, Mattsson PT, Knekt M, Westlund A, Scheffzek K, Saraste M, Svergun DI
The EMBO journal 2003 Sep 15;22(18):4616-24
The EMBO journal 2003 Sep 15;22(18):4616-24
Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production.
Horwood NJ, Mahon T, McDaid JP, Campbell J, Mano H, Brennan FM, Webster D, Foxwell BM
The Journal of experimental medicine 2003 Jun 16;197(12):1603-11
The Journal of experimental medicine 2003 Jun 16;197(12):1603-11
Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4.
Jefferies CA, Doyle S, Brunner C, Dunne A, Brint E, Wietek C, Walch E, Wirth T, O'Neill LA
The Journal of biological chemistry 2003 Jul 11;278(28):26258-64
The Journal of biological chemistry 2003 Jul 11;278(28):26258-64
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC