BS1327

antibody from Bioworld Technology, Inc
Targeting: SNAP25 bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25
Provider product page for BS1327
Western blot
Immunohistochemistry

Antibody data

Product number
BS1327 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1327, RRID:AB_1663463
Product name
SNAP 25 (E183) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 150-200 of Human SNAP 25.
Description
Syntaxins, six of which have been identified, were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF(N-ethylmaleimide-sensitive factor), SNAP 25, SNAPs (soluble NSF attachment proteins) and synap-totagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and Synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including Ï«- and ÎÛ-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exocytosis bycompeting with SNAP 25 and syntaxins for VAMP binding.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SNAP25 protein structure - BS1327 shown in red.