FNab03782

antibody from FineTest Biotech
Targeting: HCFC1 CFF, HCF-1, HCF1, HFC1, MGC70925, MRX3, PPP1R89, VCAF
Provider product page for FNab03782
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab03782 - Provider product page
Provider
FineTest Biotech
Product name
HCFC1 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase(H3K4me) and Sin3 histone deacetylase(HDAC) complexes(involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus(HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
host cell factor C1(VP16-accessory
protein)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
HCFC1 protein structure - FNab03782 shown in red.