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- Antibody Data
- Antigen structure
- References [18]
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- Product number
- 66258-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- FAK antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated FAK antibody (Cat. #66258-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2C5B9
- Vial size
- 20ul, 150ul
Submitted references MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart.
CDC37L1 acts as a suppressor of migration and proliferation in gastric cancer by down-regulating CDK6.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis.
MiR-19a/miR-96-mediated low expression of KIF26A suppresses metastasis by regulating FAK pathway in gastric cancer.
DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non-small cell lung cancer.
TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling.
Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
RSRC1 suppresses gastric cancer cell proliferation and migration by regulating PTEN expression.
Rab34 regulates adhesion, migration, and invasion of breast cancer cells.
Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility.
Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
Thakur V, Tiburcio de Freitas J, Li Y, Zhang K, Savadelis A, Bedogni B
PloS one 2021;16(7):e0253062
PloS one 2021;16(7):e0253062
CDC37L1 acts as a suppressor of migration and proliferation in gastric cancer by down-regulating CDK6.
Li L, Tao X, Li Y, Gao Y, Li Q
Journal of Cancer 2021;12(11):3145-3153
Journal of Cancer 2021;12(11):3145-3153
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
Sodium alginate/collagen/stromal cell-derived factor-1 neural scaffold loaded with BMSCs promotes neurological function recovery after traumatic brain injury.
Ma S, Zhou J, Huang T, Zhang Z, Xing Q, Zhou X, Zhang K, Yao M, Cheng T, Wang X, Wen X, Guan F
Acta biomaterialia 2021 Sep 1;131:185-197
Acta biomaterialia 2021 Sep 1;131:185-197
NOL4L, a novel nuclear protein, promotes cell proliferation and metastasis by enhancing the PI3K/AKT pathway in ovarian cancer.
Lin F, Zhou J, Li X, Wang X
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
Biochemical and biophysical research communications 2021 Jun 25;559:121-128
FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis.
Antoniades I, Kyriakou M, Charalambous A, Kalalidou K, Christodoulou A, Christoforou M, Skourides PA
Cell communication and signaling : CCS 2021 Jan 7;19(1):3
Cell communication and signaling : CCS 2021 Jan 7;19(1):3
MiR-19a/miR-96-mediated low expression of KIF26A suppresses metastasis by regulating FAK pathway in gastric cancer.
Ma RR, Zhang H, Chen HF, Zhang GH, Tian YR, Gao P
Oncogene 2021 Apr;40(14):2524-2538
Oncogene 2021 Apr;40(14):2524-2538
DHPAC, a novel microtubule depolymerizing agent, suppresses angiogenesis and vasculogenic mimicry formation of human non-small cell lung cancer.
Gong FL, Wang L, Yu LG, Dang YF, Jiang XN, Zhao L, Guo XL
Journal of cellular biochemistry 2020 Feb 14;
Journal of cellular biochemistry 2020 Feb 14;
TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling.
Wu X, Li S, Wang K, Hua W, Li S, Song Y, Zhang Y, Yang S, Yang C
Inflammation 2019 Oct;42(5):1575-1584
Inflammation 2019 Oct;42(5):1575-1584
Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.
Ritter A, Friemel A, Roth S, Kreis NN, Hoock SC, Safdar BK, Fischer K, Möllmann C, Solbach C, Louwen F, Yuan J
Cells 2019 Oct 21;8(10)
Cells 2019 Oct 21;8(10)
Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer.
Wang G, Yang Q, Li M, Zhang Y, Cai Y, Liang X, Fu Y, Xiao Z, Zhou M, Xie Z, Huang H, Huang Y, Chen Y, He Q, Peng F, Chen Z
Biology open 2019 May 13;8(5)
Biology open 2019 May 13;8(5)
RSRC1 suppresses gastric cancer cell proliferation and migration by regulating PTEN expression.
Yu S, Gautam N, Quan M, Gao Y
Molecular medicine reports 2019 Aug;20(2):1747-1753
Molecular medicine reports 2019 Aug;20(2):1747-1753
Rab34 regulates adhesion, migration, and invasion of breast cancer cells.
Sun L, Xu X, Chen Y, Zhou Y, Tan R, Qiu H, Jin L, Zhang W, Fan R, Hong W, Wang T
Oncogene 2018 Jul;37(27):3698-3714
Oncogene 2018 Jul;37(27):3698-3714
Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
Wu Q, Yu S, Chen J, Li Y, Gao Y
IUBMB life 2018 Feb;70(2):120-128
IUBMB life 2018 Feb;70(2):120-128
AmotP130 regulates Rho GTPase and decreases breast cancer cell mobility.
Chen ZL, Yang J, Shen YW, Li ST, Wang X, Lv M, Wang BY, Li P, Zhao W, Qiu RY, Liu Y, Liu PJ, Yang J
Journal of cellular and molecular medicine 2018 Apr;22(4):2390-2403
Journal of cellular and molecular medicine 2018 Apr;22(4):2390-2403
Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway.
Chen P, Lei L, Wang J, Zou X, Zhang D, Deng L, Wu D
Cancer science 2017 Jun;108(6):1157-1168
Cancer science 2017 Jun;108(6):1157-1168
Vascular protective effects of aqueous extracts of Tribulus terrestris on hypertensive endothelial injury.
Jiang YH, Guo JH, Wu S, Yang CH
Chinese journal of natural medicines 2017 Aug;15(8):606-614
Chinese journal of natural medicines 2017 Aug;15(8):606-614
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
Alekhina O, Marchese A
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
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