Antibody data
- Antibody Data
- Antigen structure
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- Product number
- Ab102794 - Provider product page
- Provider
- Aladdin Scientific Corporation
- Product name
- FAK Antibody
- Antibody type
- Polyclonal
- Description
- Rabbit anti Human FAK Antibody, Polyclonal, could be used for WB, IHC and so on.ApplicationWB: 0.5-2 µg/mLIHC: 5-20 µg/mLProtein FunctionNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
AA 798-1041
- Vial size
- 100μl,10μl,1ml,20μl,50μl
- Concentration
- Lot by Lot
- Storage
- Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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