MB0055
antibody from Bioworld Technology, Inc
Targeting: UHRF1
FLJ21925, ICBP90, Np95, RNF106, TDRD22
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MB0055 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- UHRF1 (N terminus) monoclonal antibody
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide, corresponding to the N-terminus of Human UHRF1.
- Description
- This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot detection of UHRF1 antibody in Mouse heart, 293T, HelaNE&Hela cell lysates using UHRF1 antibody (1:1000 diluted) .